first_imgPhoto: Kevin Cole Tedeschi Trucks Band continued their 2018 Wheels of Soul tour on Sunday night, stopping in Mansfield, Massachusetts for a performance at the Xfinity Center. Joined by Drive-By Truckers and The Marcus King Band, the twelve-piece offered up yet-another barn burner highlighted by a bust-out cover of the Allman Brothers Band‘s “Little Martha” and a raging encore, featuring members of the Marcus King Band for covers of Sly & The Family Stone‘s “Sing A Simple Song” and “I Want to Take You Higher”.Tedeschi Trucks Band’s headlining set kicked off with a familiar cover of Derek and the Dominos‘ “Anyday”. The next nine songs kept it close to home for the Tedeschi Trucks Band, weaving in covers of Derek Trucks Band‘s “Get What You Deserve” and the Allman Brothers’ “Little Martha”, which hadn’t been played by TTB since 2012. The Eat A Peach closing track was played at the end of every ABB show since the 1980’s, as a respectful bow to the band’s fallen leader, Duane Allman. Yesterday also marked the birthday of original ABB drummer Jaimoe, who collaborated with TTB on Friday night, and Mama A, Duane and Gregg’s mother who passed away several years ago, so the return of “Little Martha” was especially meaningful.After debuting it on Saturday night, TTB also performed their newest cover, “Going, Going, Gone”—a tune off Bob Dylan‘s 1974 Planet Waves, which was likely also used as a tribute to the late Gregg Allman, who covered the song on his final album, Southern Blood.The rest of the set wove together fan-favorite originals, including “Do I Look Worried”, their newer “Shame” which Derek Trucks recently confirmed will be on their upcoming album, “Midnight In Harlem”, and more from the band’s extensive catalog. The jam-packed setlist closed with Billy Taylor‘s “I Wish I Knew How It Would Feel To Be Free”.For the encore, Tedeschi Trucks Band returned for a version of their own “Just As Strange” from 2016’s Let Me Get By before welcoming out their guests for the evening for a Sly & The Family Stone medley. Marcus King, who’s now performed with TTB a handful of times on this tour, brought out his own keyboardist, Deshawn “D’Vibes” Alexander, and horn players Justin Johnson and Dean Mitchell to join the fun.Thanks to taper rjhesq, you can listen to the full audio below:Thanks to YouTube user Jamey Klein, you can watch video highlights from last night’s show below:“Sing A Simple Song” > “I Want To Take You Higher” w/ Marcus King, D’Vibes, Justin Johnson, Dean Mitchell“Going, Going, Gone”“Just As Strange”“I Wish I Knew How It Would Feel To Be Free”“Made Up Mind”“Right On Time”“Part Of Me”“Get What You Deserve”“Do I Look Worried”“Midnight In Harlem”Check out the full photo gallery below, courtesy of photographer Kevin Cole.Setlist: Tedeschi Trucks Band | Xfinity Center | Mansfield, MA | 7/8/18Anyday, Do I Look Worried, Get What You Deserve, Part of Me, Shame, Little Martha, Midnight In Harlem, Right On Time, Made Up My Mind, I Wish I Knew How It Would Feel To Be FreeE: Just As Strange, Sing A Simple Song, I Want To Take You Higher Load remaining images Load remaining images Photo: Kevin Colelast_img read more

first_imgHarvard scientists have solved the long-standing mystery of how some insects form germ cells, the precursors to the eggs and sperm necessary for sexual reproduction. The answer is shedding light on the evolutionary origins of a gene that has been long viewed as critical to the process.As described in a paper published Dec. 4 in Current Biology, a team of researchers led by Cassandra Extavour, associate professor of organismic and evolutionary biology, discovered that a cricket, a so-called lower insect, possesses a variation of a gene — called oskar — that has been shown to be critical to the production of germ cells in “higher” insects, particularly fruit flies. That discovery, Extavour said, suggests that the oskar gene emerged far earlier in insect evolution than researchers previously believed.“The prevailing hypothesis was that, since only higher insects appeared to possess the oskar gene, that it must have emerged after the two branches of insect evolution diverged,” Extavour said. “We found that that can’t be right. Oskar is present in both groups of insects, so it must have emerged in their last common ancestor.”Aside from rewriting science’s understanding of how germ lines evolved in insects, the finding is also shining fresh light on the importance of looking beyond the traditional models for biological research. Had her team not reached beyond the oft-used fruit fly model, Extavour said, its discovery of the evolutionary history of oskar likely would not have happened.“There are some questions, especially deep evolutionary questions, you can never get at by examining only one animal,” said Extavour, who also serves as the director of the Evo-Devo-Eco Network (EDEN), an initiative funded by the National Science Foundation aimed at providing support to researchers who work outside the traditional model organisms. “And you certainly can’t get at them by examining animals that are very far removed from their last common ancestor, as the evidence shows fruit flies are.“The whole concept of the model organism is based on the principle that what works in one organism works the same way, or a very similar way, in another organism,” Extavour said. “The more we know about biology, the more we understand that that’s not always the case.”While their findings provide an answer to a riddle that had long stumped biologists, Extavour and her colleagues began their research by asking a simple question: Because germ cells are critical to the reproduction of so many plants and animals, could there be a single genetic pathway — one that evolution never tinkered with — to create them?Scientists have long understood that higher insects such as fruit flies use a process called maternal inheritance, in which the mother loads material — including the oskar gene — into eggs before they are laid. That material, called germ plasm, later causes the cells containing it to become germ cells.Among most lower insects, however, the process of forming germ cells is completely different, Extavour said, and understanding it provided hints that the oskar gene’s original role likely had nothing to do with germ cells.While Extavour’s team found that lower insects like crickets do have a variation of the oskar gene, they were surprised to find that it appears to have little to do with forming germ cells. Unlike fruit flies, which cannot form germ cells without oskar, removing the gene from crickets has no effect on germ cell formation.“What that means is that even though oskar emerged much earlier in evolution than we suspected, this role that we’ve been talking about for more than three decades — oskar has only been talked about in the context of being a germ line gene — this may not be the ancestral role it played,” Extavour said. “Somewhere along the line, it changed jobs.”What was oskar’s original job, then, if it wasn’t to form germ cells?When the researchers examined crickets, they found the gene not in germ cells but in neural stem cells called neuroblasts, suggesting that its original role was in the nervous system. Supporting this hypothesis was their observation that removing the gene from crickets caused defects in neuron production and nervous system wiring.“Our argument is basically that in the last common ancestor of insects, the ancestral role for oskar was most likely in wiring the nervous system,” Extavour said. “Somewhere along the line, it got co-opted into this germ line pathway, and eventually rose to prominence in the hierarchy of genes that control germ cell formation.”last_img read more

first_imgWhat happens when Western secondhand clothing and message T-shirts are imported to African consumers, many from less affluent classes? Joana Choumali, a Côte d’Ivoire-based artist noted for her work embroidering directly on photographs, will explore these questions and more, backed by a fellowship at the Peabody Museum of Archaeology & Ethnology.As the 2020 Robert Gardner Fellow in Photography, Choumali will receive a $50,000 stipend to launch a project, followed by the publication of a book.Choumali plans to ground her fellowship in an “anthropology of clothing.” Her photographic and mixed-media project, “Yougou-Yougou” (Secondhand Clothing), will explore how imported Western clothing affects community identity and exposes inequalities created by colonial legacies, transnational trade, and global power relations.,“Choumali starts with a traditionally flat medium and then layers thread and fabric to add dimension, texture, color, and new meaning.” — Ilisa Barbash, the Peabody Museum’s Curator of Visual Anthropology,The artist works mainly on conceptual portraits, documentary photography, and mixed media, most recently embroidering directly on photographic images with what she calls, “a slow and meditative gesture.”“Joana Choumali’s works extend the boundaries of photography into exciting new territory,” said the Peabody’s Curator of Visual Anthropology Ilisa Barbash. “Choumali starts with a traditionally flat medium and then layers thread and fabric to add dimension, texture, color, and new meaning. What begins as an instantaneous image produced by the technology of digital photography becomes enriched, politicized, and transformed by Joana’s beautiful and painstaking hand-sewing.”,Through “Yougou-Yougou,” Choumali will investigate the sociopolitical implications of western “fast fashion” in Côte d’Ivoire, and possibly adjacent countries.“My aim is to demonstrate that through this clothing our Ivorian community (more precisely, the dynamic youth) generally appropriates culture, incorporating styles and messages into their self-presentation, imagination, and social practices.” “The phenomenon of secondhand message T-shirts provokes many questions … How much room do consumers have to maneuver between the original message (which they may not — or even want to — understand) and their own political concerns?” — Maria Anney, sociologist Choumali’s frequent collaborator, sociologist Maria Anney, explains, “During the pre-colonial and colonial eras, the regions of sub-Saharan Africa underwent massive extractions of their natural resources sent to the West, and at the same time their local markets were invaded by secondhand Western products, thus rendering Africans dependent on cheap and used imports. Many articles and social studies have produced some important data about this fact.”“The phenomenon of secondhand message T-shirts provokes many questions: Who buys these, and why? What is the influence of these messages on the social imagination of the communities who wear these secondhand clothes? How much room do consumers have to maneuver between the original message (which they may not — or even want to — understand) and their own political concerns? What does it mean to sell foreign ideologies in this way?”,Choumali’s mixed-media techniques, says Anney, “make visible the way in which social codes circulate through an object (the clothes) and an active body.” After photographing people wearing message T-shirts, Choumali says she will “manually intervene on the portraits by superimposing textiles, embroidery, and collage to create a relief effect.”“The freedom offered by this technique,” says Anney, allows Choumali to “reclaim the imposed message, inviting us to reflect on a new history or third life of these T-shirts.”Before embarking on a photography career, Choumali studied graphic arts in Casablanca, Morocco, and worked as an art director in an advertising agency.,“During these challenging times, when the arts are more important than ever in bringing us together, we are delighted to be able to continue this important program,” said Jane Pickering, the William and Muriel Seabury Howells Director of the Peabody.“Since 2007 this fellowship has supported emerging and mid-career photographers from six continents to document, as Robert Gardner put it, ‘the human condition anywhere in the world.’“I would like to extend my deepest thanks not only to Robert Gardner (1925–2014) and his wife, Adele Pressman, but also to the anonymous award committee and nominators, and to the extraordinary artists who were invited to submit proposals for this highly competitive award.” The Daily Gazette Sign up for daily emails to get the latest Harvard news. Relatedcenter_img Photographer documents the region through the lens of the area’s natural resources Framing the Caspian Sealast_img read more

first_imgDell Technologies Data Manager supports all three services mentioned; AKS, GKE and EKS. The infrastructure is made up of Data Manager on-premises or in the public cloud and PowerProtect DD Virtual Edition as storage or their storage disks as target(s). By having DD Virtual Edition as a target it creates an extension of flexibility for the administrators to protect clusters from an on-premises storage disk, hosted on the service instance in the public cloud.  In addition to the rich service features that are provided by the end platforms, all the enterprise-features are additionally accessible via Data Manager. These extra features include policy creation, application consistency, cluster restores between clusters, and self-service. With multi-cloud models of development, developers can simply deploy applications in a cloud that provides the best services for the application; AWS RDS (Relational Database Service) and Google ML libraries are such examples. Orchestration comes in through management on-premises and connecting Kubernetes clusters to seamlessly migrate the data between clusters powered by DD Virtual Edition at the cloud target; thereby achieving a true multi-cloud experience wherein YOU the consumer meet SLAs in record setting timeframes! As the “race to embrace” Kubernetes unfolds, major “hyperscalers” such as Microsoft Azure, Google Cloud and Amazon AWS have provided their users’ services to deploy and manage them. They are portals for easier management, pre-built templates, cloud portability, and more agile processes within a cloud structure. Respectively, they are referred to as Azure Kubernetes Services, Google Kubernetes Engine, and Elastic Kubernetes Service. These services provide low-cost playgrounds for developers to generate secure platforms in the cloud and change customer end user experience with fewer overhead costs and without interruption. In some ways, the services mimic the agile and seamless foundation that Kubernetes provides a developer where the customer and end user receive faster, bug-free outputs.During everyday activities that consumers enjoy including ordering coffee to go, hailing an Uber, using Instacart for grocery shopping or monitoring a delivery; somewhere there are unseen applications running these tasks. With agility and mobile application development “on the fly”, data protection and data management tools enable faster, more trustworthy ways to span updates to the edge without disruption. While there are many use case examples of cloud development, Dell Technologies’ PowerProtect Data Manager provides the momentum to finish the race.last_img read more

first_imgEastern oysters, which are native to the estuaries on the Georgia coast, reproduce in the summer. The bags of shells will serve as a scaffold and habitat for these young oysters, which are called “spat.” The goal is to have all of the bags of oyster shells in place in time for this year’s spat to find their new home. “We want to get the shells out there as soon as possible so that the spat can settle into the new habitat,” Risse said. “It’s usually two or three years down the road before you get a fully established oyster reef. You’ll see the bags this summer, but hopefully, by winter, you’ll see new oysters setting up along the tops. In two or three years, you won’t see the bags at all.” A living shoreline created by oysters is superior to a concrete or rock bulkhead commonly used to secure an eroding coastal shoreline because of its resilience and the ecosystem services it provides. An oyster reef can provide a habitat for 70 to 80 different species of aquatic animals and helps to increase the quality of estuary waters. “We’re putting out a habitat and a food source that’s going to house and feed other species,” Risse said. “Also, oysters will respond to sea level rise. Oysters will be able to move up with the water level, where a bulkhead would just be swamped.” Georgia 4-H is building the shoreline with support from UGA Marine Extension, Georgia Sea Grant and the UGA Office of the Vice President for Public Service and Outreach. Coastal Civil Engineering was hired by Georgia 4-H to develop the construction plan. The Carl Vinson Institute of Government, The Nature Conservancy, the Five Star and Urban Waters Restoration Grant Program and the City of Tybee Island are supporting this project. Georgia 4-H is recruiting an army of bivalves to help ensure the future of the organization’s coastal environmental education center. The organization is working with University of Georgia Marine Extension to encourage new oyster beds along the marshy shoreline at Burton 4-H Center on Tybee Island, Georgia. In early April, dozens of volunteers spent a Saturday morning filling bags with oyster shells. These bagged shells will be placed along the shoreline to create a new habitat for wild oysters and spur the creation of new oyster reefs along the marsh’s edge. This new living shoreline, built from six truckloads of oyster shells along about 500 feet of marsh front, should resist erosion, create and improve the wildlife habitat, improve water quality and help mitigate sea level rise. “A couple of years ago, we realized that the Horse Pen Creek was encroaching on most of the buildings at Burton 4-H Center,” said Arch Smith, director of Georgia 4-H, which is part of UGA Cooperative Extension. “We began working with engineers to develop a solution to reduce the erosion of the creek bank and settled upon a solution that adds an educational component as well.” Building the living shoreline will provide an opportunity for 4-H environmental education program instructors to use it as a teaching tool for the 8,000 school students that visit Burton 4-H Center annually and study coastal habitats and issues. Burton 4-H Center is one of five facilities operated by Georgia 4-H that provide environmental education programs. The process of designing and getting permitting approval for the living shoreline project started more than a year ago and will likely take several years for it to be fully stabilized as a natural oyster reef, said Mark Risse, director of UGA Marine Extension. Volunteers packed discarded oyster shells, a byproduct of the seafood industry, into perforated, Naltex (a marine-safe plastic) bags. The bags will then be packed onto the shoreline. The old shells will create the skeleton for a new oyster bed, which looks like a mound of oysters protruding from the marsh’s muddy bottom. last_img read more

first_imgThe UK’s Pension Protection Fund (PPF) has raised £150m (€206m) from the sale of a property company previously owned by the industry-wide schemes for the coal sector.The lifeboat fund agreed to sell 75.1% of Harworth Estates Property Group to Coalfield Resources (CfR), which traded as UK Coal prior to an ultimately failed restructuring meant to save the remaining UK-based coal pits from closure.As part of the deal, the PPF will be issued with a 25% stake in Coalfield and paid a further £97m in cash.The sale price of £150m accounts to a 20% discount on Harworth’s net asset value at the end of 2014. Coalfield chairman Jonson Cox welcomed the deal, noting it would complete the firm’s transformation into a brownfield property developer.“We will be in a strong position to take full advantage of our proven skills in the property and regeneration markets and to deliver value,” he said.“I would like to thank our existing and new shareholders for their support in achieving an important milestone for the business.”Malcolm Weir, the PPF’s head of restructuring and insolvency, was also positive about the agreement.“We are pleased that, by working closely with CfR, we have been able deliver a significant uplift in value from the Harworth Estates holding for the PPF,” he said. “We look forward to continuing to work with CfR to generate further returns for the PPF and other shareholders from the PPF’s ongoing shareholding in CfR.”Harworth Estates was established by UK Coal in 2012, with the Industry-Wide Mineworkers’ Pension Scheme (IWMPS) and the Industry-Wide Coal Staff Superannuation Scheme (IWCSSS) granted majority shares in the new firm in lieu of further deficit contribution payments. The restructure was signed off by regulators in an attempt to save UK Coal from insolvency.However, the company eventually went insolvent, triggering the schemes’ entry into the PPF, after a fire closed one of its coal pits.last_img read more

first_imgHerald Sun 29 Nov 2011Childcare kids have more temper tantrums and a worse dose of the “terrible twos” than other children, new Australian research shows. A study of more than 5000 toddlers has found behavioural problems equivalent to an 11-month developmental delay in children aged two and three who are in childcare for more than 20 hours a week. Behavioural problems include frustration, moodiness, screaming and the inability to play consistently with one toy.On the flipside, day-care kids were also found to be more sociable and outgoing with strangers. The negative impact of care is particularly felt in children with richer parents with higher levels of education. But these problems were not present in children in centres that had higher numbers of carers to children, according to the Australian National University study, to be published next month in the Economics of Education Review journal. read more

first_img 20 Views   no discussions Share Could genetically modified stem cells be used to treat genetic diseases?Two of the holy grails of medicine – stem cell technology and precision gene therapy – have been united for the first time in humans, say scientists. It means patients with a genetic disease could, one day, be treated with their own cells.A study in Nature corrected a mutation in stem cells made from a patient with a liver disease.Researchers said this was a “critical step” towards devising treatments, but safety tests were still needed.At the moment, stem cells created from a patient with a genetic illness cannot be used to cure the disease as those cells would also contain the corrupted genetic code.Scientists, at the Wellcome Trust Sanger Institute and the University of Cambridge, were working on cirrhotic liver disease.It is caused by a change to a single pair of letters, out of the six billion which make up the genetic code. As a result, a protein which protects the body from damage, antitrypsin, cannot escape from the liver where it is made. The illness is one of the most common genetic diseases, affecting one in 2,000 people in Europe.The only solution is a liver transplant, but this requires a lifetime of drugs to prevent organ rejection.The research group took a skin cell from a patient and converted it to a stem cell. A molecular scalpel was used to cut out the single mutation and insert the right letter – correcting the genetic fault.The stem cells were then turned into liver cells. One of the lead researchers, Prof David Lomas, said: “They functioned beautifully with normal secretion and function”.When the cells were placed into mice, they were still working correctly six weeks later.‘Enormous potential’Prof Lomas said if this could be developed into a therapy it would be preferable to liver transplant as the patient would not need to take immunosuppressant drugs.He told the BBC that the technique was “ridiculously hard,” yet “the potential is enormous, but only time will tell”.Further animal studies and human clinical trials would be needed before any treatment as “the key thing is safety”.For example, concerns have been raised about “induced” stem cells being prone to expressing cancer causing genes.Prof Robin Ali, from University College London and the Medical Research Council’s stem cell translational research committee, said: “It’s very interesting.“Most gene therapy is not correcting the gene, it’s introducing a new copy of the gene, what’s exciting is that this corrects.“The big problem with individualised medicine is the cost – that is one of the major barriers.”By James GallagherHealth reporter, BBC News Sharing is caring! Tweetcenter_img HealthLifestyle Gene therapy and stem cells unite by: – October 14, 2011 Share Sharelast_img read more

first_imgA Turkish military cargo plane prepares to evacuate the car-bomb explosion victims in Aden Abdulle International Airport in Mogadishu, Somalia on Dec. 29. REUTERS/FEISAL OMAR MOGADISHU – A Turkish military cargoplane has landed in the Somali capital on Sunday to evacuate people who werebadly wounded in a truck bombing that killed at least 90 people, including twoTurkish nationals. Somali information minister MohamedAbdi Hayir Mareye said 10 Somalis who were badly wounded in Saturday’s blastwould be evacuated to Turkey – which had sent 24 doctors to treat thosewounded.   The plane also brought emergencymedical staff and supplies, the Turkish embassy said. Saturday’s blast, at a busy checkpointduring rush hour in Mogadishu, was the deadliest in Somalia in over two years.No one immediately claimed responsibility, although authorities blamed alQaeda-linked Islamist group al Shabaab.(Reuters)last_img read more

first_imgWe are all familiar with the large tarps that major league baseball teams use to keep the infield dry.  They also use a drying compound when a particular area gets damp.  But what about those diamonds that can’t afford these large tarps and expensive drying compounds?When I took the American Legion Baseball Team to Madison one year for a double header, we found the infield very wet.  Since we had already driven to Madison, the team there said “we will find a way to get this diamond dry”.  Since we were at the city park, they decided to borrow a barrel of racing fuel stored in a shed by the diamond.  This fuel belonged to the Miss Madison racing boat.  They poured the fuel on the dirt part of the  infield and lit a match to it.  Fifteen minutes later the infield was bone dry and ready for play.  I don’t know who footed the bill for this barrel of very expensive racing fuel.Recently at a college World Series game the grounds keepers used tennis squeegees to roll the water off the outfield.  As the water was pushed passed the foul lines, it was scooped up and thrown on the warning track.  Fortunately, they found a lot of squeegees and many willing hands to push them because the outfield looked like a lake before they started.  It is amazing what inquiring minds can come up with if you want to play a game bad enough.last_img read more